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Among communities from the areas where the plant is native, khat chewing has a history as a social custom dating back thousands of years analogous to the use of coca leaves in South America and betel nut in Asia.It is a controlled substance in some countries, such as Canada, Germany, the United Kingdom, and the United States, while its production, sale, and consumption are legal in other nations, including Djibouti, Kenya, Uganda, Ethiopia, Somalia and Yemen.

However, the attribution was disputed by reports showing the plant extracts from fresh leaves contained another substance more behaviourally active than cathine.

In 1975, the related alkaloid cathinone was isolated, and its absolute configuration was established in 1978.

Khat was ranked 17th in dependence, 20th in physical harm, and 20th in social harm.

Individuals become very talkative under the influence of the plant.

A good khat plant can be harvested four times a year, providing a year-long source of income for the farmer.

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